TRIM25 in the Regulation of the Antiviral Innate Immunity

TRIM25 in the Regulation of the Antiviral Innate Immunity

TRIM25 is an E3 ubiquitin ligase enzyme that is involved in various cellular processes, including regulation of the innate immune response against viruses. TRIM25-mediated ubiquitination of the cytosolic pattern recognition receptor RIG-I is an essential step for initiation of the intracellular anti...

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Bibliographic Details
Main Authors: María Martín-Vicente, Luz M. Medrano, Salvador Resino, Adolfo García-Sastre, Isidoro Martínez
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
TRIM25
innate immunity
ubiquitination
virus
E3 ubiquitin ligase
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01187/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01187/full

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