Functional promoter -31G>C variant in survivin gene is associated with risk and progression of renal cell cancer in a Chinese population.

Functional promoter -31G>C variant in survivin gene is associated with risk and progression of renal cell cancer in a Chinese population.

BACKGROUND: Survivin is an inhibitor of apoptosis protein and is involved in the occurrence and progression of human malignancies. Recently, a functional polymorphism (-31G>C, rs9904341) in the promoter of survivin has been shown to influence its expression and confer susceptibility to different...

Full description

Bibliographic Details
Main Authors: Chao Qin, Qiang Cao, Pu Li, Xiaobing Ju, Meilin Wang, Jiawei Chen, Yilong Wu, Xiaoxin Meng, Jian Zhu, Zhengdong Zhang, Qiang Lu, Changjun Yin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3266235?pdf=render

Internet

http://europepmc.org/articles/PMC3266235?pdf=render

Similar Items