Influence of Statins locally applied from orthopedic implants on osseous integration

Influence of Statins locally applied from orthopedic implants on osseous integration

<p>Abstract</p> <p>Background</p> <p>Simvastatin increases the expression of bone morphogenetic protein 2 (BMP-2) in osteoblasts, therefore it is important to investigate the influence of statins on bone formation, fracture healing and implant integration. The aim of th...

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Bibliographic Details
Main Authors: Pauly Stephan, Back David A, Kaeppler Kathrin, Haas Norbert P, Schmidmaier Gerhard, Wildemann Britt
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Musculoskeletal Disorders
Subjects:
Statins
Simvastatin
Implant integration
BMP
Local application
Online Access:http://www.biomedcentral.com/1471-2474/13/208

Internet

http://www.biomedcentral.com/1471-2474/13/208

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