Secretoglobin 3A2 eliminates human cancer cells through pyroptosis

Abstract Non-canonical inflammasome activation that recognizes intracellular lipopolysaccharide (LPS) causes pyroptosis, the inflammatory death of innate immune cells. The role of pyroptosis in innate immune cells is to rapidly eliminate pathogen-infected cells and limit the replication niche in the...

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Bibliographic Details
Main Authors: Shigetoshi Yokoyama, Shun Nakayama, Lei Xu, Aprile L. Pilon, Shioko Kimura
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-020-00385-w