Zebrafish Model as a Screen to Prevent Cyst Inflation in Autosomal Dominant Polycystic Kidney Disease

Zebrafish Model as a Screen to Prevent Cyst Inflation in Autosomal Dominant Polycystic Kidney Disease

In autosomal dominant polycystic kidney disease (ADPKD), kidney cyst growth requires the recruitment of CFTR (cystic fibrosis transmembrane conductance regulator), the chloride channel that is defective in cystic fibrosis. We have been studying cyst inflation using the zebrafish Kupffer’s vesicle (K...

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Bibliographic Details
Main Authors: Inês Oliveira, Raquel Jacinto, Sara Pestana, Fernando Nolasco, Joaquim Calado, Susana Santos Lopes, Mónica Roxo-Rosa
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
autosomal dominant polycystic kidney disease (ADPKD)
cystic fibrosis transmembrane conductance regulator (CFTR)
Kupffer’s vesicle (KV)
polycystin-2 (PC2)
Online Access:https://www.mdpi.com/1422-0067/22/16/9013

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https://www.mdpi.com/1422-0067/22/16/9013

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