Partial LPL deletions: rare copy-number variants contributing towards severe hypertriglyceridemia

Partial LPL deletions: rare copy-number variants contributing towards severe hypertriglyceridemia

Severe hypertriglyceridemia (HTG) is a relatively common form of dyslipidemia with a complex pathophysiology and serious health complications. HTG can develop in the presence of rare genetic factors disrupting genes involved in the triglyceride (TG) metabolic pathway, including large-scale copy-numb...

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Bibliographic Details
Main Authors: Jacqueline S. Dron, Jian Wang, Adam D. McIntyre, Henian Cao, John F. Robinson, P. Barton Duell, Priya Manjoo, James Feng, Irina Movsesyan, Mary J. Malloy, Clive R. Pullinger, John P. Kane, Robert A. Hegele
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Journal of Lipid Research
Subjects:
bioinformatic analysis
diagnostic tools
dyslipidemias
genetic testing
human genetics
next-generation sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520322938

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http://www.sciencedirect.com/science/article/pii/S0022227520322938

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