Synthetic genistein derivatives as modulators of glycosaminoglycan storage

Synthetic genistein derivatives as modulators of glycosaminoglycan storage

<p>Abstract</p> <p>Background</p> <p>Mucopolysaccharidoses (MPS) are severe metabolic disorders caused by accumulation of undegraded glycosaminoglycans (GAGs) in lysosomes due to defects in certain lysosomal hydrolases. Substrate reduction therapy (SRT) has been propose...

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Bibliographic Details
Main Authors: Kloska Anna, Narajczyk Magdalena, Jakóbkiewicz-Banecka Joanna, Grynkiewicz Grzegorz, Szeja Wiesław, Gabig-Cimińska Magdalena, Węgrzyn Grzegorz
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Translational Medicine
Subjects:
Mucopolysaccharidoses
Substrate reduction therapy
Synthetic derivatives of genistein
Online Access:http://www.translational-medicine.com/content/10/1/153

Internet

http://www.translational-medicine.com/content/10/1/153

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