Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer
Abstract Epithelial-to-mesenchymal transition (EMT) is fundamental to both normal tissue development and cancer progression. We hypothesized that EMT plasticity defines a range of metabolic phenotypes and that individual breast epithelial metabolic phenotypes are likely to fall within this phenotypi...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-09-01
|
| Series: | npj Systems Biology and Applications |
| Online Access: | https://doi.org/10.1038/s41540-021-00195-5 |