Plaques Formed by Mutagenized Viral Populations Have Elevated Coinfection Frequencies

The plaque assay is a common technique used to measure virus concentrations and is based upon the principle that each plaque represents a single infectious unit. As such, the number of plaques is expected to correlate linearly with the virus dilution plated, and each plaque should be formed by a sin...

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Bibliographic Details
Main Authors: Elizabeth R. Aguilera, Andrea K. Erickson, Palmy R. Jesudhasan, Christopher M. Robinson, Julie K. Pfeiffer, Mark R. Denison
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/2/e02020-16