Role of Parkin and endurance training on mitochondrial turnover in skeletal muscle

Abstract Background Parkin is a ubiquitin ligase that is involved in the selective removal of dysfunctional mitochondria. This process is termed mitophagy and can assist in mitochondrial quality control. Endurance training can produce adaptations in skeletal muscle toward a more oxidative phenotype,...

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Bibliographic Details
Main Authors: Chris Chin Wah Chen, Avigail T. Erlich, David A. Hood
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Skeletal Muscle
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13395-018-0157-y