Renal thrombotic microangiopathy in mice with combined deletion of endocytic recycling regulators EHD3 and EHD4.

Eps15 Homology Domain-containing 3 (EHD3), a member of the EHD protein family that regulates endocytic recycling, is the first protein reported to be specifically expressed in the glomerular endothelium in the kidney; therefore we generated Ehd3(-/-) mice and assessed renal development and pathology...

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Main Authors: Manju George, Mark A Rainey, Mayumi Naramura, Kirk W Foster, Melissa S Holzapfel, Laura L Willoughby, GuoGuang Ying, Rasna M Goswami, Channabasavaiah B Gurumurthy, Vimla Band, Simon C Satchell, Hamid Band
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3052385?pdf=render