Numerical Investigations of Hepatic Spheroids Metabolic Reactions in a Perfusion Bioreactor

Miniaturized culture systems of hepatic cells are emerging as a strong tool facilitating studies related to liver diseases and drug discovery. However, the experimental optimization of various parameters involved in the operation of these systems is time-consuming and expensive. Hence, developing nu...

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Bibliographic Details
Main Authors: Fatemeh Sharifi, Bahar Firoozabadi, Keikhosrow Firoozbakhsh
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00221/full