Novel Gliclazide Electrosprayed Nano-Solid Dispersions: Physicochemical Characterization and Dissolution Evaluation

Novel Gliclazide Electrosprayed Nano-Solid Dispersions: Physicochemical Characterization and Dissolution Evaluation

Purpose: In the current study, electrospraying was directed as a novel alternative approach to improve the physicochemical attributes of gliclazide (GLC), as a poorly water-soluble drug, by creating nanocrystalline/amorphous solid dispersions (ESSs). Methods: ESSs were formulated using Eudragit® RS...

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Bibliographic Details
Main Authors: Khosro Adibkia, Solmaz Ghajar, Karim Osouli-Bostanabad, Niloufar Balaei, Shahram Emami, Mohammad Barzegar-Jalali
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2019-06-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Amorphous solid dispersions
Eudragit® RS100
Electrospray
Gliclazide
In vitro evaluation
Nanocrystalline
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-22801

Internet

https://apb.tbzmed.ac.ir/PDF/apb-22801

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