A genotype imputation method for de-identified haplotype reference information by using recurrent neural network

Genotype imputation estimates the genotypes of unobserved variants using the genotype data of other observed variants based on a collection of haplotypes for thousands of individuals, which is known as a haplotype reference panel. In general, more accurate imputation results were obtained using a la...

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Bibliographic Details
Main Authors: Kaname Kojima, Shu Tadaka, Fumiki Katsuoka, Gen Tamiya, Masayuki Yamamoto, Kengo Kinoshita, Ferhat Ay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529210/?tool=EBI