Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays.

Alternative mRNA processing mechanisms lead to multiple transcripts (i.e. splice isoforms) of a given gene which may have distinct biological functions. Microarrays like Affymetrix GeneChips measure mRNA expression of genes using sets of nucleotide probes. Until recently probe sets were not designed...

Full description

Bibliographic Details
Main Authors: Anton G Moll, Maja T Lindenmeyer, Matthias Kretzler, Peter J Nelson, Ralf Zimmer, Clemens D Cohen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2650090?pdf=render