Flipping the transcriptional switch from myelin inhibition to axon growth in the CNS

Poor regeneration of severed axons in the central nervous system (CNS) limits functional recovery. Regeneration failure involves an interplay of inhibitory environmental elements and the growth state of the neuron. To find internal changes in gene expression that might overcome inhibitory environme...

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Bibliographic Details
Main Authors: Jason B Carmel, Wise eYoung, Ronald P Hart
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
DRG
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00034/full