Maximum efficacy of mesenchymal stem cells in rat model of renal ischemia-reperfusion injury: renal artery administration with optimal numbers.

BACKGROUNDS: Despite the potential therapeutic benefits, cell therapy in renal ischemia-reperfusion (I/R) injury is currently limited by low rates of cell engraftment after systemic delivery. In this study, we investigate whether locally administration through renal artery can enhance the migration...

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Bibliographic Details
Main Authors: Jieru Cai, Xiaofang Yu, Rende Xu, Yi Fang, Xiaoqin Qian, Shaopeng Liu, Jie Teng, Xiaoqiang Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3956922?pdf=render