SNP2Structure: A Public and Versatile Resource for Mapping and Three-Dimensional Modeling of Missense SNPs on Human Protein Structures

SNP2Structure: A Public and Versatile Resource for Mapping and Three-Dimensional Modeling of Missense SNPs on Human Protein Structures

One of the long-standing challenges in biology is to understand how non-synonymous single nucleotide polymorphisms (nsSNPs) change protein structure and further affect their function. While it is impractical to solve all the mutated protein structures experimentally, it is quite feasible to model th...

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Bibliographic Details
Main Authors: Difei Wang, Lei Song, Varun Singh, Shruti Rao, Lin An, Subha Madhavan
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Active site mutations
Protein structure
Molecular modeling
Disease causing SNPs
SNP database
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037015000434

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http://www.sciencedirect.com/science/article/pii/S2001037015000434

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