Plasma-based microsatellite instability detection strategy to guide immune checkpoint blockade treatment

Background Microsatellite instability (MSI) represents the first pan-cancer biomarker approved to guide immune checkpoint blockade (ICB) treatment. However its widespread testing, especially outside of gastrointestinal cancer, is hampered by tissue availability.Methods An algorithm for detecting MSI...

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Bibliographic Details
Main Authors: Lin Shen, Chan Gao, Yifan Zhou, Jing Gao, Xiaochen Zhao, Jifang Gong, Zhenghang Wang, Xicheng Wang, Zhongwu Li, Dalei Wang, Xiaofang Li, Yuezong Bai
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e001297.full