In silico Design and Synthesis of Tetrahydropyrimidinones and Tetrahydropyrimidinethiones as Potential Thymidylate Kinase Inhibitors Exerting Anti-TB Activity Against Mycobacterium tuberculosis

In silico Design and Synthesis of Tetrahydropyrimidinones and Tetrahydropyrimidinethiones as Potential Thymidylate Kinase Inhibitors Exerting Anti-TB Activity Against Mycobacterium tuberculosis

Katharigatta N Venugopala, 1, 2 Christophe Tratrat, 1 Melendhran Pillay, 3 Sandeep Chandrashekharappa, 4 Omar Husham Ahmed Al-Attraqchi, 5 Bandar E Aldhubiab, 1 Mahesh Attimarad, 1 Osama I Alwassil, 6 Anroop B Nair, 1 Nagaraja Sreeharsha, 1 Rashmi Venugopala, 7 Mohamed A Morsy, 1, 8 Michelyne Haroun...

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Bibliographic Details
Main Authors: Venugopala KN, Tratrat C, Pillay M, Chandrashekharappa S, Al-Attraqchi OHA, Aldhubiab BE, Attimarad M, Alwassil OI, Nair AB, Sreeharsha N, Venugopala R, Morsy MA, Haroun M, Kumalo HM, Odhav B, Mlisana K
Format: Article
Language:English
Published: Dove Medical Press 2020-03-01
Series:Drug Design, Development and Therapy
Subjects:
thymidylate kinase inhibitors
tetrahydropyrimidinones
tetrahydropyrimidinethiones
multidrug resistance
mycobacterium tuberculosis
molecular modeling.
Online Access:https://www.dovepress.com/in-silico-design-and-synthesis-of-tetrahydropyrimidinones-and-tetrahyd-peer-reviewed-article-DDDT

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https://www.dovepress.com/in-silico-design-and-synthesis-of-tetrahydropyrimidinones-and-tetrahyd-peer-reviewed-article-DDDT

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