Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety

Dysregulated prefrontal control over amygdala has been implicated in the etiology of stress-related psychiatric disorders. Here, the authors show that the dysregulation preferentially occurs in amygdala neurons that are mono- but not bi-directionally connected with dorsomedial prefrontal cortex.

Bibliographic Details
Main Authors: Wei-Zhu Liu, Wen-Hua Zhang, Zhi-Heng Zheng, Jia-Xin Zou, Xiao-Xuan Liu, Shou-He Huang, Wen-Jie You, Ye He, Jun-Yu Zhang, Xiao-Dong Wang, Bing-Xing Pan
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15920-7