HSV-1-derived amplicon vectors: recent technological improvements and remaining difficulties - a review
Amplicons are defective and non-integrative vectors derived from herpes simplex virus type 1. As the vector genome carries no virus genes, amplicons are both non-toxic for the infected cells and non-pathogenic for the inoculated organisms. In addition, the large transgenic capacity of amplicons, whi...
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| Format: | Article |
| Language: | English |
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Instituto Oswaldo Cruz, Ministério da Saúde
2009-05-01
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| Series: | Memórias do Instituto Oswaldo Cruz. |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000300002 |