Identifying genes with tri-modal association with survival and tumor grade in cancer patients

Identifying genes with tri-modal association with survival and tumor grade in cancer patients

Abstract Background Previous cancer genomics studies focused on searching for novel oncogenes and tumor suppressor genes whose abundance is positively or negatively correlated with end-point observation, such as survival or tumor grade. This approach may potentially miss some truly functional genes...

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Bibliographic Details
Main Authors: Minzhe Zhang, Tao Wang, Rosa Sirianni, Philip W. Shaul, Yang Xie
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Bioinformatics
Subjects:
Expectation maximization
Oncogene
Tumor suppressor gene
Survival
Breast Cancer
Online Access:http://link.springer.com/article/10.1186/s12859-018-2582-7

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http://link.springer.com/article/10.1186/s12859-018-2582-7

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