Potential Application of Tregitopes as Immunomodulating Agents in Multiple Sclerosis

The induction of immunologic tolerance is an important clinical goal in autoimmunity. CD4+ regulatory T (Treg) cells, defined by the expression of the transcription factor forkhead box P3 (FoxP3), play a central role in the control of autoimmune responses. Quantitative and qualitative defects of Tre...

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Bibliographic Details
Main Authors: Wassim Elyaman, Samia J. Khoury, David W. Scott, Anne S. De Groot
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Neurology Research International
Online Access:http://dx.doi.org/10.1155/2011/256460