Unsupervised phenotyping of sepsis using nonnegative matrix factorization of temporal trends from a multivariate panel of physiological measurements
Abstract Background Sepsis is a highly lethal and heterogeneous disease. Utilization of an unsupervised method may identify novel clinical phenotypes that lead to targeted therapies and improved care. Methods Our objective was to derive clinically relevant sepsis phenotypes from a multivariate panel...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
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Series: | BMC Medical Informatics and Decision Making |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12911-021-01460-7 |