Amplified genes may be overexpressed, unchanged, or downregulated in cervical cancer cell lines.

Amplified genes may be overexpressed, unchanged, or downregulated in cervical cancer cell lines.

Several copy number-altered regions (CNAs) have been identified in the genome of cervical cancer, notably, amplifications of 3q and 5p. However, the contribution of copy-number alterations to cervical carcinogenesis is unresolved because genome-wide there exists a lack of correlation between copy-nu...

Full description

Bibliographic Details
Main Authors: Oscar Vazquez-Mena, Ingrid Medina-Martinez, Eligia Juárez-Torres, Valeria Barrón, Ana Espinosa, Nicolás Villegas-Sepulveda, Laura Gómez-Laguna, Karem Nieto-Martínez, Lorena Orozco, Edgar Roman-Basaure, Sergio Muñoz Cortez, Manuel Borges Ibañez, Carlos Venegas-Vega, Mariano Guardado-Estrada, Angélica Rangel-López, Susana Kofman, Jaime Berumen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3296745?pdf=render

Internet

http://europepmc.org/articles/PMC3296745?pdf=render

Similar Items