Cobalt Protoporpyhrin Reduces Caspase-3,-7 Enzyme Activity in Neonatal Porcine Islets, But Does Not Inhibit Cell Death Induced by TNF-α

Cobalt Protoporpyhrin Reduces Caspase-3,-7 Enzyme Activity in Neonatal Porcine Islets, But Does Not Inhibit Cell Death Induced by TNF-α

Apoptotic phenomena observed in vitro following isolation and following transplantation contribute significantly to islet graft loss. Strategies to reduce apoptosis of islet tissue prior to and posttransplantation may improve graft survival and function and reduce the amount of tissue necessary to a...

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Bibliographic Details
Main Authors: Erika Bosio Ph.D, Michela Seveso, Arben Dedja, Giovanni Luca, Mario Calvitti, Riccardo Calafiore, Paolo Rigotti, Roberto Busetto, Ermanno Ancona, Emanuele Cozzi
Format: Article
Language:English
Published: SAGE Publishing 2008-06-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368908786092784

Internet

https://doi.org/10.3727/096368908786092784

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