Non-pulsatile blood flow is associated with enhanced cerebrovascular carbon dioxide reactivity and an attenuated relationship between cerebral blood flow and regional brain oxygenation

Abstract Background Systemic blood flow in patients on extracorporeal assist devices is frequently not or only minimally pulsatile. Loss of pulsatile brain perfusion, however, has been implicated in neurological complications. Furthermore, the adverse effects of absent pulsatility on the cerebral mi...

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Main Authors: Cecilia Maria Veraar, Harald Rinösl, Karina Kühn, Keso Skhirtladze-Dworschak, Alessia Felli, Mohamed Mouhieddine, Johannes Menger, Ekaterina Pataraia, Hendrik Jan Ankersmit, Martin Dworschak
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Critical Care
Subjects:
Online Access:https://doi.org/10.1186/s13054-019-2671-7