Assessment of reproducibility and biological variability of fasting and postprandial plasma metabolite concentrations using 1H NMR spectroscopy.

<h4>Introduction</h4>It is crucial to understand the factors that introduce variability before applying metabolomics to clinical and biomarker research.<h4>Objectives</h4>We quantified technical and biological variability of both fasting and postprandial metabolite concentrat...

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Bibliographic Details
Main Authors: Ruifang Li-Gao, David A Hughes, Saskia le Cessie, Renée de Mutsert, Martin den Heijer, Frits R Rosendaal, Ko Willems van Dijk, Nicholas J Timpson, Dennis O Mook-Kanamori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218549