Hiding in plain sight: Gene panel and genetic markers reveal 26-year undiagnosed tumor-induced osteomalacia of the rib concurrently misdiagnosed as X-linked hypophosphatemia

Hiding in plain sight: Gene panel and genetic markers reveal 26-year undiagnosed tumor-induced osteomalacia of the rib concurrently misdiagnosed as X-linked hypophosphatemia

Tumor-induced osteomalacia (TIO), caused by phosphaturic mesenchymal tumors (PMTs), is a rare paraneoplastic syndrome characterized by frequent bone fractures, bone pain, muscle weakness, and affected gait. These tumors typically secrete high levels of Fibroblastic Growth Factor 23 (FGF23), a hormon...

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Bibliographic Details
Main Authors: Juan M. Colazo, BSc, Joseph A. DeCorte, BS, Erin A. Gillaspie, MD, MPH, Andrew L. Folpe, MD, Kathryn M. Dahir, MD
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Bone Reports
Subjects:
Tumor-induced osteomalacia
TIO
Fibroblast growth factor 23
FGF23
Paraneoplastic
Phosphaturic mesenchymal tumor
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187220305040

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http://www.sciencedirect.com/science/article/pii/S2352187220305040

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