HDAC4-myogenin axis as an important marker of HD-related skeletal muscle atrophy.
Skeletal muscle remodelling and contractile dysfunction occur through both acute and chronic disease processes. These include the accumulation of insoluble aggregates of misfolded amyloid proteins that is a pathological feature of Huntington's disease (HD). While HD has been described primarily...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-03-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4352047?pdf=render |