A Mutational Hotspot and Strong Selection Contribute to the Order of Mutations Selected for during Escherichia coli Adaptation to the Gut.

The relative role of drift versus selection underlying the evolution of bacterial species within the gut microbiota remains poorly understood. The large sizes of bacterial populations in this environment suggest that even adaptive mutations with weak effects, thought to be the most frequently occurr...

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Bibliographic Details
Main Authors: Marta Lourenço, Ricardo S Ramiro, Daniela Güleresi, João Barroso-Batista, Karina B Xavier, Isabel Gordo, Ana Sousa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5094792?pdf=render