Antiparasitic Sesquiterpenes from the Cameroonian Spice Scleria striatinux and Preliminary In Vitro and In Silico DMPK Assessment

Antiparasitic Sesquiterpenes from the Cameroonian Spice Scleria striatinux and Preliminary In Vitro and In Silico DMPK Assessment

Abstract The antiparasitic activity and preliminary in vitro and in silico drug metabolism and pharmacokinetic (DMPK) assessment of six isomeric sesquiterpenes (1–6), isolated from the Cameroonian spice Scleria striatinux De Wild (Cyperaceae) is reported. The study was prompted by the observation th...

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Bibliographic Details
Main Authors: Kennedy D. Nyongbela, Fidele Ntie-Kang, Thomas R. Hoye, Simon M. N. Efange
Format: Article
Language:English
Published: SpringerOpen 2017-04-01
Series:Natural Products and Bioprospecting
Subjects:
Sesquiterpenes
Pharmacokinetics
Drug metabolism
Scleria striatinux
Online Access:http://link.springer.com/article/10.1007/s13659-017-0125-y

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http://link.springer.com/article/10.1007/s13659-017-0125-y

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