Successful production of genome-edited rats by the rGONAD method

Successful production of genome-edited rats by the rGONAD method

Abstract Background Recent progress in development of the CRISPR/Cas9 system has been shown to be an efficient gene-editing technology in various organisms. We recently developed a novel method called Genome-editing via Oviductal Nucleic Acids Delivery (GONAD) in mice; a novel in vivo genome editing...

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Bibliographic Details
Main Authors: Tomoe Kobayashi, Masumi Namba, Takayuki Koyano, Masaki Fukushima, Masahiro Sato, Masato Ohtsuka, Makoto Matsuyama
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Biotechnology
Subjects:
CRISPR/Cas9
i-GONAD
rGONAD
Rat
Knock-out
Knock-in
Online Access:http://link.springer.com/article/10.1186/s12896-018-0430-5

Internet

http://link.springer.com/article/10.1186/s12896-018-0430-5

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