A CASE REPORT OF AN ULTRA-RAPID METABOLIZER ON DEPOT FORMULATIONS OF RISPERIDONE AND HALOPERIDOL AND REFLECTIONS ON METABOLIC PATHWAYS
Polycyclic aromatic hydrocarbons (PAH) in tobacco are potent inducers of Cytochrome P450 (CYP) 1A2, which metabolizes a plenty of drugs including antipsychotics such as olanzapine or clozapine. With regard to haloperidol and risperidone, CYP3A4 is supposed to be the major isoenzyme. We present the c...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
University in Nis, Faculty of Medicine
2014-09-01
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| Series: | Acta Medica Medianae |
| Subjects: | |
| Online Access: | http://publisher.medfak.ni.ac.rs/2014-html/3-broj/Koch%20Horst%20-Case%20report.pdf |