Effects of thyroxine exposure on osteogenesis in mouse calvarial pre-osteoblasts.

The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes. At present, very little is known about the r...

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Bibliographic Details
Main Authors: James J Cray, Kameron Khaksarfard, Seth M Weinberg, Mohammed Elsalanty, Jack C Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720861?pdf=render