Chronic antidepressant treatment rescues abnormally reduced REM sleep theta power in socially defeated rats

Chronic antidepressant treatment rescues abnormally reduced REM sleep theta power in socially defeated rats

Abstract The effects of chronic antidepressant (AD) treatment on sleep disturbances in rodent chronic stress models have not been thoroughly investigated. Here, we show that chronic social defeat stress (SDS) in rats induces prolonged social avoidance, alterations in sleep architecture (increased to...

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Bibliographic Details
Main Authors: Yoshiki Matsuda, Nobuyuki Ozawa, Takiko Shinozaki, Kazuhisa Aoki, Naomi Nihonmatsu-Kikuchi, Toshikazu Shinba, Yoshitaka Tatebayashi
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96094-0

Internet

https://doi.org/10.1038/s41598-021-96094-0

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