Increased endoplasmic reticulum stress response is involved in clopidogrel-induced apoptosis of gastric epithelial cells.

Increased endoplasmic reticulum stress response is involved in clopidogrel-induced apoptosis of gastric epithelial cells.

The widespread use of clopidogrel alone or in combination with aspirin may result in gastrointestinal mucosal injury, clinically represented as recurrent ulceration and bleeding complications. Our recent work suggested that clopidogrel significantly induced human gastric epithelial cell (GES-1) apop...

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Bibliographic Details
Main Authors: Hai-Lu Wu, Zhao-Tao Duan, Zong-Dan Jiang, Wei-Jun Cao, Zhi-Bing Wang, Ke-Wei Hu, Xin Gao, Shu-Kui Wang, Bang-Shun He, Zhen-Yu Zhang, Hong-Guang Xie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3772828?pdf=render

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http://europepmc.org/articles/PMC3772828?pdf=render

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