Airway disease phenotypes in animal models of cystic fibrosis

Airway disease phenotypes in animal models of cystic fibrosis

Abstract In humans, cystic fibrosis (CF) lung disease is characterised by chronic infection, inflammation, airway remodelling, and mucus obstruction. A lack of pulmonary manifestations in CF mouse models has hindered investigations of airway disease pathogenesis, as well as the development and testi...

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Bibliographic Details
Main Authors: Alexandra McCarron, Martin Donnelley, David Parsons
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Respiratory Research
Subjects:
Cystic fibrosis
Animal models
Lung disease
Pathology
Online Access:http://link.springer.com/article/10.1186/s12931-018-0750-y

Internet

http://link.springer.com/article/10.1186/s12931-018-0750-y

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