The Drosophila MI-2 chromatin-remodeling factor regulates higher-order chromatin structure and cohesin dynamics in vivo.

The Drosophila MI-2 chromatin-remodeling factor regulates higher-order chromatin structure and cohesin dynamics in vivo.

dMi-2 is a highly conserved ATP-dependent chromatin-remodeling factor that regulates transcription and cell fates by altering the structure or positioning of nucleosomes. Here we report an unanticipated role for dMi-2 in the regulation of higher-order chromatin structure in Drosophila. Loss of dMi-2...

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Bibliographic Details
Main Authors: Barbara Fasulo, Renate Deuring, Magdalena Murawska, Maria Gause, Kristel M Dorighi, Cheri A Schaaf, Dale Dorsett, Alexander Brehm, John W Tamkun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3415455?pdf=render

Internet

http://europepmc.org/articles/PMC3415455?pdf=render

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