DNA methylation-mediated repression of exosomal miR-652-5p expression promotes oesophageal squamous cell carcinoma aggressiveness by targeting PARG and VEGF pathways.

DNA methylation-mediated repression of exosomal miR-652-5p expression promotes oesophageal squamous cell carcinoma aggressiveness by targeting PARG and VEGF pathways.

Exosomal microRNAs (miRNAs) have been recently shown to play vital regulatory and communication roles in cancers. In this study, we showed that the expression levels of miR-652-5p in tumour tissues and serum samples of oesophageal squamous cell carcinoma (OSCC) patients were lower compared to non-tu...

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Bibliographic Details
Main Authors: Peng Gao, Dan Wang, Meiyue Liu, Siyuan Chen, Zhao Yang, Jie Zhang, Huan Wang, Yi Niu, Wei Wang, Jilong Yang, Guogui Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008592

Internet

https://doi.org/10.1371/journal.pgen.1008592

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