Relationship Between Plasma Osteopontin and Arginine Pathway Metabolites in Patients With Overt Coronary Artery Disease

Relationship Between Plasma Osteopontin and Arginine Pathway Metabolites in Patients With Overt Coronary Artery Disease

IntroductionOsteopontin (OPN) is involved in ectopic calcification. Its circulating form is upregulated in coronary artery disease (CAD) patients. Circulating OPN levels positively correlate with oxidative stress, one of the major triggers of endothelial dysfunction. Endothelial dysfunction is, in t...

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Bibliographic Details
Main Authors: Donato Moschetta, Matteo Nicola Dario Di Minno, Benedetta Porro, Gianluca L. Perrucci, Vincenza Valerio, Valentina Alfieri, Ilaria Massaiu, Alexander N. Orekhov, Alessandro Di Minno, Paola Songia, Viviana Cavalca, Veronika A. Myasoedova, Paolo Poggio
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Physiology
Subjects:
atherosclerosis
endothelial dysfunction
OPN
nitric oxide
citrulline
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00982/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00982/full

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