The receptor for advanced glycation endproducts (RAGE) does not contribute to pathology in a mouse mesenteric ischemia/reperfusion-induced injury model

The receptor for advanced glycation endproducts (RAGE) can engage a diverse class of ligands and contribute to the immune and inflammatory response to infection and injury. It is known to be a pathogenic receptor in many inflammatory diseases, including ischemia/reperfusion (IR) injuries in several...

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Bibliographic Details
Main Authors: Mike C.L. Wu, Timothy D. Gilmour, Susanna eMantovani, Trent M. Woodruff
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Immunology
Subjects:
C3a
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00614/full