Statins stimulate arachidonic acid release and prostaglandin I<sub>2 </sub>production in rat liver cells

<p>Abstract</p> <p>Statins inhibit 3-hydroxy-3-methylglutaryl (HMG-CoA) reductase, the rate limiting step in cholesterol synthesis. They are, therefore, used clinically to lower cholesterol and prevent atherosclerosis. Statins have beneficial effects on multiple organ systems. Some...

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Bibliographic Details
Main Author: Levine Lawrence
Format: Article
Language:English
Published: BMC 2003-03-01
Series:Lipids in Health and Disease
Online Access:http://www.Lipidworld.com/content/2/1/1