Statins stimulate arachidonic acid release and prostaglandin I<sub>2 </sub>production in rat liver cells
<p>Abstract</p> <p>Statins inhibit 3-hydroxy-3-methylglutaryl (HMG-CoA) reductase, the rate limiting step in cholesterol synthesis. They are, therefore, used clinically to lower cholesterol and prevent atherosclerosis. Statins have beneficial effects on multiple organ systems. Some...
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Format: | Article |
Language: | English |
Published: |
BMC
2003-03-01
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Series: | Lipids in Health and Disease |
Online Access: | http://www.Lipidworld.com/content/2/1/1 |