Induced pluripotent stem cells as a cellular model for studying Down Syndrome

Down Syndrome (DS), or Trisomy 21 Syndrome, is one of the most common genetic diseases. It is a chromosomal abnormality caused by a duplication of chromosome 21. DS patients show the presence of a third copy (or a partial third copy) of chromosome 21 (trisomy), as result of meiotic errors. These pat...

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Bibliographic Details
Main Authors: Brigida AL, Siniscalco D
Format: Article
Language:English
Published: GN Corporation Limited 2016-11-01
Series:Journal of Stem Cells and Regenerative Medicine
Subjects:
Online Access:http://www.pubstemcell.com/monthly/012020200009.htm