Preparation and preclinical evaluation of a 68Ga-labelled c(RGDfK) conjugate comprising the bifunctional chelator NODIA-Me

Preparation and preclinical evaluation of a 68Ga-labelled c(RGDfK) conjugate comprising the bifunctional chelator NODIA-Me

Abstract Background We recently developed a chelating platform based on the macrocycle 1,4,7-triazacyclononane with up to three, five-membered azaheterocyclic arms for the development of 68Ga- and 64Cu-based radiopharmaceuticals. Here, a 68Ga-labelled conjugate comprising the bifunctional chelator N...

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Bibliographic Details
Main Authors: Tilman Läppchen, Jason P. Holland, Yvonne Kiefer, Mark D. Bartholomä
Format: Article
Language:English
Published: SpringerOpen 2018-05-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Gallium-68
Integrins
αvß3
PET imaging
Bifunctional chelator
NODIA-Me
Online Access:http://link.springer.com/article/10.1186/s41181-018-0043-2

Internet

http://link.springer.com/article/10.1186/s41181-018-0043-2

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