D2 dopamine receptor subtype-mediated hyperactivity and amphetamine responses in a model of ADHD

Low doses of psychostimulants produce beneficial behavioral effects in ADHD patients but the mechanisms underlying the response are not understood. Here we use the hyperactive mouse mutant coloboma to identify D2-like dopamine receptor subtypes that mediate the hyperactivity and response to amphetam...

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Bibliographic Details
Main Authors: Xueliang Fan, Ming Xu, Ellen J. Hess
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109002861