The CpG island methylator phenotype is concordant between primary colorectal carcinoma and matched distant metastases

The CpG island methylator phenotype is concordant between primary colorectal carcinoma and matched distant metastases

Abstract Background The CpG island methylator phenotype (CIMP) in stage III colon cancer (CRC) has been associated with improved survival after treatment with adjuvant irinotecan-based chemotherapy. In this analysis, we determine whether CIMP status in the primary CRC is concordant with the CIMP sta...

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Bibliographic Details
Main Authors: Stacey A. Cohen, Ming Yu, Kelsey Baker, Mary Redman, Chen Wu, Tai J. Heinzerling, Ralph M. Wirtz, Elpida Charalambous, George Pentheroudakis, Vassiliki Kotoula, Konstantine T. Kalogeras, George Fountzilas, William M. Grady
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Clinical Epigenetics
Subjects:
CIMP
DNA methylation
Colorectal cancer
Metastatic
Biomarker
Online Access:http://link.springer.com/article/10.1186/s13148-017-0347-1

Internet

http://link.springer.com/article/10.1186/s13148-017-0347-1

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