Confounding effect of blood volume and body mass index on blood neurofilament light chain levels

Abstract Blood Neurofilament light chain (NfL) has been suggested as a promising biomarker in several neurological conditions. Since blood NfL is the consequence of leaked NfL from the cerebrospinal fluid, differences in individuals’ Body Mass Index (BMI) or blood volume (BV) might affect its correl...

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Bibliographic Details
Main Authors: Ali Manouchehrinia, Fredrik Piehl, Jan Hillert, Jens Kuhle, Lars Alfredsson, Tomas Olsson, Ingrid Kockum
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.50972