Long-term use of interferon-β in multiple sclerosis increases Vδ1−Vδ2−Vγ9− γδ T cells that are associated with a better outcome

Long-term use of interferon-β in multiple sclerosis increases Vδ1−Vδ2−Vγ9− γδ T cells that are associated with a better outcome

Abstract Background We previously reported that Vδ2+Vγ9+ γδ T cells were significantly decreased in multiple sclerosis (MS) patients without disease-modifying therapies (untreated MS) and were negatively correlated with Expanded Disability Status Scale (EDSS) scores, suggesting protective roles of V...

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Bibliographic Details
Main Authors: Guzailiayi Maimaitijiang, Mitsuru Watanabe, Koji Shinoda, Noriko Isobe, Yuri Nakamura, Katsuhisa Masaki, Takuya Matsushita, Yasunobu Yoshikai, Jun-ichi Kira
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Neuroinflammation
Subjects:
Multiple sclerosis
Disease-modifying therapy
Interferon-β
γδ T cell
Online Access:http://link.springer.com/article/10.1186/s12974-019-1574-5

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http://link.springer.com/article/10.1186/s12974-019-1574-5

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